Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.

Complement receptor 1 (CR1, CD35) and complement receptor 2 (CR2, CD21) have been implicated as regulators of B-cell activation. We explored the role of these receptors in the development of humoral immunity by generating CR1- and CR2-deficient mice using gene-targeting techniques. These mice have n...

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Detalhes bibliográficos
Main Authors: Molina, H, Holers, V M, Li, B, Fung, Y, Mariathasan, S, Goellner, J, Strauss-Schoenberger, J, Karr, R W, Chaplin, D D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39612/
https://ncbi.nlm.nih.gov/pubmed/8622941
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