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An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA
Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific antibodies (DSA) binding donor Class I and II HLA (HLA-I and HLA-II) expressed on endothelial cells. While F(ab′)(2) portions of DSA cause cellular activation and proliferation,...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Am J Transplant |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Blackwell Publishing Ltd
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654252/ https://ncbi.nlm.nih.gov/pubmed/25904443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13273 |
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