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The Perfect Storm: HLA Antibodies, Complement, FcγRs and Endothelium in Transplant Rejection
The pathophysiology of antibody-mediated rejection (AMR) in solid organ transplants is multi-faceted and predominantly caused by antibodies directed against polymorphic donor human leukocyte antigens (HLA). Despite the clearly detrimental impact of HLA antibodies (HLA-Ab) on graft function and survi...
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Publicado no: | Trends Mol Med |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4424065/ https://ncbi.nlm.nih.gov/pubmed/25801125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2015.02.004 |
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