載入...
Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera From Subjects Dosed With the Anti-C1s Monoclonal Antibody TNT009—Results from a Randomized First-in-Human Phase 1 Trial
BACKGROUND: Complement may play a key role in antibody-mediated rejection. A promising therapeutic approach may be classical pathway (CP) inhibition at the level of early component C1. METHODS: In this first-in-human, double-blind, randomized placebo-controlled phase 1 trial, we evaluated the safety...
Na minha lista:
| 發表在: | Transplantation |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Lippincott Williams & Wilkins
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610566/ https://ncbi.nlm.nih.gov/pubmed/28926521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001804 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|