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Paroxetine suppresses recombinant human P2X7 responses

P2X7 receptor (P2X7) activity may link inflammation to depressive disorders. Genetic variants of human P2X7 have been linked with major depression and bipolar disorders, and the P2X7 knockout mouse has been shown to exhibit anti-depressive-like behaviour. P2X7 is an ATP-gated ion channel and is a ma...

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Publicado en:Purinergic Signal
Autores principales: Dao-Ung, Phuong, Skarratt, Kristen K., Fuller, Stephen J., Stokes, Leanne
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648795/
https://ncbi.nlm.nih.gov/pubmed/26341077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-015-9467-2
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