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Genetics of the P2X7 receptor and human disease

The P2RX7 gene is highly polymorphic, and many single nucleotide polymorphisms (SNPs) underlie the wide variation observed in P2X7 receptor responses. We review the discovery of those non-synonymous SNPs that affect receptor function and compare their frequencies in different ethnic populations. Ana...

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Detalhes bibliográficos
Main Authors: Fuller, Stephen J., Stokes, Leanne, Skarratt, Kristen K., Gu, Ben J., Wiley, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686826/
https://ncbi.nlm.nih.gov/pubmed/19319666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9136-4
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