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Genetics of the P2X7 receptor and human disease
The P2RX7 gene is highly polymorphic, and many single nucleotide polymorphisms (SNPs) underlie the wide variation observed in P2X7 receptor responses. We review the discovery of those non-synonymous SNPs that affect receptor function and compare their frequencies in different ethnic populations. Ana...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686826/ https://ncbi.nlm.nih.gov/pubmed/19319666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9136-4 |
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