Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome

INTRODUCTION: The aim of this study was to examine the association between functional polymorphisms in the pro-inflammatory P2X7 receptor and the Ro/La autoantibody response in primary Sjögren's syndrome (pSS). METHODS: Twelve functional P2RX7 polymorphisms were genotyped in 114 pSS patients fu...

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Detalhes bibliográficos
Main Authors: Lester, Susan, Stokes, Leanne, Skarratt, Kristen K, Gu, Ben J, Sivils, Kathy L, Lessard, Christopher J, Wiley, James S, Rischmueller, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979150/
https://ncbi.nlm.nih.gov/pubmed/23819992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4248
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