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Revisiting the Idea That Amyloid-β Peptide Acts as an Agonist for P2X7

The P2X7 receptor (P2X7) is a cell surface ligand-gated ion channel, activated by its physiological nucleotide agonist ATP and a synthetic analog (BzATP). However, it has also been suggested that there may be structurally unrelated, non-nucleotide agonists such as the amyloidogenic β peptide. Here w...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Bibič, Lučka, Stokes, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530339/
https://ncbi.nlm.nih.gov/pubmed/33071753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00166
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