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Effects of antagonists at the human recombinant P2X(7) receptor

1. We have used whole-cell patch clamping methods to examine the properties of the recombinant human P2X(7) (P2Z) receptor stably expressed in HEK-293 cells. 2. In an extracellular solution with lowered concentrations of divalent cations (zero Mg(2+) and 0.5 mM Ca(2+)), both ATP and the nucleotide a...

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Detalles Bibliográficos
Main Authors: Chessell, I P, Michel, A D, Humphrey, P P A
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565513/
https://ncbi.nlm.nih.gov/pubmed/9720806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701958
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