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Antagonist effects on human P2X(7) receptor-mediated cellular accumulation of YO-PRO-1

1. We have examined the interaction of P2 antagonists with the human P2X(7) receptor by studying their effect on 2′ and 3′-O-benzoyl-benzoyl-ATP (DbATP) stimulated cellular accumulation of the fluorescent, DNA binding dye, YO-PRO-1 (MW=375Da). 2. In suspensions of HEK293 cells expressing human recom...

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Detalhes bibliográficos
Main Authors: Michel, A D, Kaur, R, Chessell, I P, Humphrey, P P A
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572117/
https://ncbi.nlm.nih.gov/pubmed/10821778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703368
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