Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit

Understanding the biosynthetic mechanism of the atypical polyketide extender unit is important for the development of bioactive natural products. Reveromycin (RM) derivatives produced by Streptomyces sp. SN-593 possess several aliphatic extender units. Here, we studied the molecular basis of 2-alkyl...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Miyazawa, Takeshi, Takahashi, Shunji, Kawata, Akihiro, Panthee, Suresh, Hayashi, Teruo, Shimizu, Takeshi, Nogawa, Toshihiko, Osada, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646404/
https://ncbi.nlm.nih.gov/pubmed/26378232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677195
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars