A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units

Type I modular polyketide synthases assemble diverse bioactive natural products. Such multienzymes typically use malonyl and methylmalonyl-CoA building blocks for polyketide chain assembly. However, in several cases more exotic alkylmalonyl-CoA extender units are also known to be incorporated. In al...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ray, Lauren, Valentic, Timothy R., Miyazawa, Takeshi, Withall, David M., Song, Lijiang, Milligan, Jacob C., Osada, Hiroyuki, Takahashi, Shunji, Tsai, Shiou-Chuan, Challis, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187497/
https://ncbi.nlm.nih.gov/pubmed/28000660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13609
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados