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Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase

Chemo- and stereoselective reductions are important reactions in chemistry and biology, and reductases from biological sources are increasingly applied in organic synthesis. In contrast, carboxylases are used only sporadically. We recently described crotonyl-CoA carboxylase/reductase, which catalyze...

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Detalhes bibliográficos
Main Authors: Erb, Tobias J., Brecht, Volker, Fuchs, Georg, Müller, Michael, Alber, Birgit E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689996/
https://ncbi.nlm.nih.gov/pubmed/19458256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903939106
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