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Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase

Chemo- and stereoselective reductions are important reactions in chemistry and biology, and reductases from biological sources are increasingly applied in organic synthesis. In contrast, carboxylases are used only sporadically. We recently described crotonyl-CoA carboxylase/reductase, which catalyze...

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Autors principals: Erb, Tobias J., Brecht, Volker, Fuchs, Georg, Müller, Michael, Alber, Birgit E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689996/
https://ncbi.nlm.nih.gov/pubmed/19458256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903939106
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