लोड हो रहा है...
SPOP E3 Ubiquitin Ligase Adaptor Epigenetically Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase.
The SPOP gene, encoding an E3 ubiquitin ligase adaptor, is frequently mutated in a number of cancer types such as prostate. However, the mechanisms by which SPOP functions as a tumor suppressor remain poorly understood. Here we show that SPOP promotes senescence, an important tumor suppression mecha...
में बचाया:
| में प्रकाशित: | Cell Rep |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
|
| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4644472/ https://ncbi.nlm.nih.gov/pubmed/26527005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.083 |
| टैग : |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|