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Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis

A diverse set of innate immune mechanisms protects cells from viral infections. The APOBEC3 family of DNA cytosine deaminases is an integral part of these defenses. For instance, APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H would have the potential to destroy HIV-1 complementary DNA replication interm...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Anderson, Brett D., Harris, Reuben S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643775/
https://ncbi.nlm.nih.gov/pubmed/26601257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500296
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