Discovery of 5-Substituted Tetrahydronaphthalen-2yl) methyl with N-phenyl-N-(piperidin-4-yl)propionamide Derivatives as Potent Opioid Receptor Ligands

A new series of novel opioid ligands have been designed and synthesized based on the 4-anilidopiperidine scaffold containing a 5-substituted tetrahydronaphthalen-2yl-methyl group with different N-phenyl-N-(piperidin-4-yl)propionamide derivatives to study the biological effects of these substituents...

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Publicado en:Bioorg Med Chem
Autores principales: Deekonda, Srinivas, Wugalter, Lauren, Kulkarni, Vinod, Rankin, David, Largent-Milnes, Tally M., Davis, Peg, Bassirirad, Neemah M., Lai, Josephine, Vanderah, Todd W., Porreca, Frank, Hruby, Victor J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642887/
https://ncbi.nlm.nih.gov/pubmed/26299827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.07.071
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