Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl) propionamide derivatives: Synthesis and biological evaluations

N-Phenyl-N-(piperidin-2-ylmethyl)propionamide based bivalent ligands are unexplored for the design of opioid based ligands. Two series of hybrid molecules bearing N-phenyl-N-(piperidin-2-ylmethyl)propionamide derived small molecules conjugated with an enkephalin analogues with and without a linker (...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Deekonda, Srinivas, Cole, Jacob, Sunna, Sydney, Rankin, David, Largent-Milnes, Tally M., Davis, Peg, BassiriRad, Neemah M., Lai, Josephine, Vanderah, Todd W., Porecca, Frank, Hruby, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873255/
https://ncbi.nlm.nih.gov/pubmed/26611918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.10.081
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