An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease

Mutations in the gene for LRRK2 are the most common cause of familial Parkinson’s disease (PD) and patients with these mutations manifest clinical features that are indistinguishable from those of the more common sporadic form. Thus, investigations of disease mechanisms based on disease-causing LRRK...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Tagliaferro, Patricia, Kareva, Tatyana, Oo, Tinmarla F, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640977/
https://ncbi.nlm.nih.gov/pubmed/26192625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.07.009
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