Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson’s disease

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson’s disease. We created a LRRK2 transgenic mouse model that recapitulates cardinal features of the disease: an age-dependent and levodopa-responsive slowness of movement associated with diminished dopamine...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Li, Yanping, Liu, Wencheng, Oo, Tinmarla F, Wang, Lei, Tang, Yi, Jackson-Lewis, Vernice, Zhou, Chun, Geghman, Kindiya, Bogdanov, Mikhail, Przedborski, Serge, Beal, M Flint, Burke, Robert E, Li, Chenjian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845930/
https://ncbi.nlm.nih.gov/pubmed/19503083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2349
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller