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An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease

Mutations in the gene for LRRK2 are the most common cause of familial Parkinson’s disease (PD) and patients with these mutations manifest clinical features that are indistinguishable from those of the more common sporadic form. Thus, investigations of disease mechanisms based on disease-causing LRRK...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Tagliaferro, Patricia, Kareva, Tatyana, Oo, Tinmarla F, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640977/
https://ncbi.nlm.nih.gov/pubmed/26192625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.07.009
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