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An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease

Mutations in the gene for LRRK2 are the most common cause of familial Parkinson’s disease (PD) and patients with these mutations manifest clinical features that are indistinguishable from those of the more common sporadic form. Thus, investigations of disease mechanisms based on disease-causing LRRK...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Tagliaferro, Patricia, Kareva, Tatyana, Oo, Tinmarla F, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640977/
https://ncbi.nlm.nih.gov/pubmed/26192625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.07.009
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