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Transgenic LRRK2(R1441G) rats–a model for Parkinson disease?

Parkinson disease (PD) is the most common movement disorder, characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra. While the cause of this disease is largely unknown, a rare autosomal dominant familial form of PD is caused by a genetic mutation in the leucine...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Shaikh, Komal T., Yang, Alvin, Youshin, Ekaterina, Schmid, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435452/
https://ncbi.nlm.nih.gov/pubmed/26020005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.945
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