AAV Transduction of Dopamine Neurons With Constitutively Active Rheb Protects From Neurodegeneration and Mediates Axon Regrowth

There are currently no therapies that provide either protection or restoration of neuronal function for adult-onset neurodegenerative diseases such as Parkinson's disease (PD). Many clinical efforts to provide such benefits by infusion of neurotrophic factors have failed, in spite of robust eff...

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Hlavní autoři: Kim, Sang Ryong, Kareva, Tatyana, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277224/
https://ncbi.nlm.nih.gov/pubmed/22008911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.213
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