AAV Transduction of Dopamine Neurons With Constitutively Active Rheb Protects From Neurodegeneration and Mediates Axon Regrowth

There are currently no therapies that provide either protection or restoration of neuronal function for adult-onset neurodegenerative diseases such as Parkinson's disease (PD). Many clinical efforts to provide such benefits by infusion of neurotrophic factors have failed, in spite of robust eff...

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Bibliografiske detaljer
Main Authors:	Kim, Sang Ryong, Kareva, Tatyana, Yarygina, Olga, Kholodilov, Nikolai, Burke, Robert E
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2012
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3277224/ https://ncbi.nlm.nih.gov/pubmed/22008911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.213
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AAV Transduction of Dopamine Neurons With Constitutively Active Rheb Protects From Neurodegeneration and Mediates Axon Regrowth

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