In Vivo AAV1 Transduction With hRheb(S16H) Protects Hippocampal Neurons by BDNF Production

Recent evidence has shown that Ras homolog enriched in brain (Rheb) is dysregulated in Alzheimer's disease (AD) brains. However, it is still unclear whether Rheb activation contributes to the survival and protection of hippocampal neurons in the adult brain. To assess the effects of active Rheb...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Jeon, Min-Tae, Nam, Jin Han, Shin, Won-Ho, Leem, Eunju, Jeong, Kyoung Hoon, Jung, Un Ju, Bae, Young-Seuk, Jin, Young-Ho, Kholodilov, Nikolai, Burke, Robert E, Lee, Seok-Geun, Jin, Byung Kwan, Kim, Sang Ryong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351465/
https://ncbi.nlm.nih.gov/pubmed/25502903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.241
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