In Vivo AAV1 Transduction With hRheb(S16H) Protects Hippocampal Neurons by BDNF Production

Recent evidence has shown that Ras homolog enriched in brain (Rheb) is dysregulated in Alzheimer's disease (AD) brains. However, it is still unclear whether Rheb activation contributes to the survival and protection of hippocampal neurons in the adult brain. To assess the effects of active Rheb...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Jeon, Min-Tae, Nam, Jin Han, Shin, Won-Ho, Leem, Eunju, Jeong, Kyoung Hoon, Jung, Un Ju, Bae, Young-Seuk, Jin, Young-Ho, Kholodilov, Nikolai, Burke, Robert E, Lee, Seok-Geun, Jin, Byung Kwan, Kim, Sang Ryong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351465/
https://ncbi.nlm.nih.gov/pubmed/25502903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.241
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