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Therapeutic Potential of AAV1-Rheb(S16H) Transduction Against Alzheimer’s Disease

We recently reported that adeno-associated virus serotype 1-constitutively active Ras homolog enriched in brain [AAV1-Rheb(S16H)] transduction of hippocampal neurons could induce neuron-astroglia interactions in the rat hippocampus in vivo, resulting in neuroprotection. However, it remains uncertain...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Moon, Gyeong Joon, Kim, Sehwan, Jeon, Min-Tae, Lee, Kea Joo, Jang, Il-Sung, Nakamura, Michiko, Kim, Sang Ryong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947419/
https://ncbi.nlm.nih.gov/pubmed/31766645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8122053
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