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Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9

RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in...

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Bibliografische gegevens
Gepubliceerd in:Bone Res
Hoofdauteurs: Kohn, Anat, Rutkowski, Timothy P, Liu, Zhaoyang, Mirando, Anthony J, Zuscik, Michael J, O’Keefe, Regis J, Hilton, Matthew J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640428/
https://ncbi.nlm.nih.gov/pubmed/26558140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2015.21
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