Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9

RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in...

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Udgivet i:Bone Res
Main Authors: Kohn, Anat, Rutkowski, Timothy P, Liu, Zhaoyang, Mirando, Anthony J, Zuscik, Michael J, O’Keefe, Regis J, Hilton, Matthew J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640428/
https://ncbi.nlm.nih.gov/pubmed/26558140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2015.21
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