RBPjκ-dependent Notch signaling is required for articular cartilage and joint maintenance

OBJECTIVE: Osteoarthritis (OA) is a degenerative disease resulting in severe joint cartilage destruction and disability. While the mechanisms underlying the development and progression of OA are poorly understood, gene mutations have been identified within cartilage-related signaling molecules impli...

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Main Authors: Mirando, Anthony J., Liu, Zhaoyang, Moore, Tyler, Lang, Alexandra, Kohn, Anat, Osinski, Alana M., O’Keefe, Regis J., Mooney, Robert A., Zuscik, Michael J., Hilton, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038327/
https://ncbi.nlm.nih.gov/pubmed/23839930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38076
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