Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9

RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in...

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Опубликовано в: :Bone Res
Главные авторы: Kohn, Anat, Rutkowski, Timothy P, Liu, Zhaoyang, Mirando, Anthony J, Zuscik, Michael J, O’Keefe, Regis J, Hilton, Matthew J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640428/
https://ncbi.nlm.nih.gov/pubmed/26558140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2015.21
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