P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest

Neutral sphingomyelinase-2 (nSMase2) is a ceramide-generating enzyme that has been implicated in growth arrest, apoptosis and exosome secretion. Although previous studies have reported transcriptional upregulation of nSMase2 in response to daunorubicin, through Sp1 and Sp3 transcription factors, the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shamseddine, A A, Clarke, C J, Carroll, B, Airola, M V, Mohammed, S, Rella, A, Obeid, L M, Hannun, Y A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632297/
https://ncbi.nlm.nih.gov/pubmed/26512957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.268
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados