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Roles and regulation of Neutral Sphingomyelinase-2 in cellular and pathological processes

Our understanding of the functions of ceramide signaling has advanced tremendously over the past decade. In this review, we focus on the roles and regulation of neutral sphingomyelinase 2 (nSMase2), an enzyme that generates the bioactive lipid ceramide through the hydrolysis of the membrane lipid sp...

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Pubblicato in:Adv Biol Regul
Autori principali: Shamseddine, Achraf A., Airola, Michael V., Hannun, Yusuf A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684640/
https://ncbi.nlm.nih.gov/pubmed/25465297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2014.10.002
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