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Roles and regulation of Neutral Sphingomyelinase-2 in cellular and pathological processes

Our understanding of the functions of ceramide signaling has advanced tremendously over the past decade. In this review, we focus on the roles and regulation of neutral sphingomyelinase 2 (nSMase2), an enzyme that generates the bioactive lipid ceramide through the hydrolysis of the membrane lipid sp...

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Detalhes bibliográficos
Publicado no:Adv Biol Regul
Main Authors: Shamseddine, Achraf A., Airola, Michael V., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684640/
https://ncbi.nlm.nih.gov/pubmed/25465297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2014.10.002
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