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Roles and regulation of Neutral Sphingomyelinase-2 in cellular and pathological processes

Our understanding of the functions of ceramide signaling has advanced tremendously over the past decade. In this review, we focus on the roles and regulation of neutral sphingomyelinase 2 (nSMase2), an enzyme that generates the bioactive lipid ceramide through the hydrolysis of the membrane lipid sp...

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Detalles Bibliográficos
Publicado en:Adv Biol Regul
Main Authors: Shamseddine, Achraf A., Airola, Michael V., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684640/
https://ncbi.nlm.nih.gov/pubmed/25465297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2014.10.002
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