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A CT-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer’s disease and affects SNCA expression
INTRODUCTION: We recently showed that tagging-SNPs across the SNCA locus were significantly associated with increased risk for LB pathology in AD cases. However, the actual genetic variant(s) that underlie the observed associations remain elusive. METHODS: We used a bioinformatics algorithm to catal...
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| Pubblicato in: | Alzheimers Dement |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4630109/ https://ncbi.nlm.nih.gov/pubmed/26079410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.05.011 |
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