The effect of SNCA 3′ region on the levels of SNCA-112 splicing variant

Genetic variability at the 3′ region of SNCA locus has been repeatedly associated with susceptibility to sporadic Parkinson’s disease (PD). Accumulated evidence emphasizes the importance of SNCA dosage and expression levels in PD pathogenesis. However, the mechanism through which the 3′ region of SN...

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Bibliografiske detaljer
Main Authors: McCarthy, Jeanette J., Linnertz, Colton, Saucier, Laura, Burke, James R., Hulette, Christine M., Welsh-Bohmer, Kathleen A., Chiba-Falek, Ornit
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030669/
https://ncbi.nlm.nih.gov/pubmed/21046180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-010-0263-4
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