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The effect of SNCA 3′ region on the levels of SNCA-112 splicing variant

Genetic variability at the 3′ region of SNCA locus has been repeatedly associated with susceptibility to sporadic Parkinson’s disease (PD). Accumulated evidence emphasizes the importance of SNCA dosage and expression levels in PD pathogenesis. However, the mechanism through which the 3′ region of SN...

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Autores principales: McCarthy, Jeanette J., Linnertz, Colton, Saucier, Laura, Burke, James R., Hulette, Christine M., Welsh-Bohmer, Kathleen A., Chiba-Falek, Ornit
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030669/
https://ncbi.nlm.nih.gov/pubmed/21046180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-010-0263-4
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