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Genetic Regulation of α-Synuclein mRNA Expression in Various Human Brain Tissues

Genetic variability across the SNCA locus has been repeatedly associated with susceptibility to sporadic Parkinson's disease (PD). Accumulated evidence emphasizes the importance of SNCA dosage and expression levels in PD pathogenesis. However whether genetic variability in the SNCA gene modulat...

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Detalhes bibliográficos
Main Authors: Linnertz, Colton, Saucier, Laura, Ge, Dongliang, Cronin, Kenneth D., Burke, James R., Browndyke, Jeffrey N., Hulette, Christine M., Welsh-Bohmer, Kathleen A., Chiba-Falek, Ornit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759540/
https://ncbi.nlm.nih.gov/pubmed/19834617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007480
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