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Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA
Thymine DNA Glycosylase (TDG) performs essential functions in maintaining genetic integrity and epigenetic regulation. Initiating base excision repair, TDG removes thymine from mutagenic G·T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymeth...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627079/ https://ncbi.nlm.nih.gov/pubmed/26358812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv890 |
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