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Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA
Thymine DNA Glycosylase (TDG) performs essential functions in maintaining genetic integrity and epigenetic regulation. Initiating base excision repair, TDG removes thymine from mutagenic G·T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymeth...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627079/ https://ncbi.nlm.nih.gov/pubmed/26358812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv890 |
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