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Excision of 5-carboxylcytosine by Thymine DNA Glycosylase

5-methylcytosine (mC) is an epigenetic mark that is written by methyltransferases, erased through passive and active mechanisms, and impacts transcription, development, diseases including cancer, and aging. Active DNA demethylation involves TET-mediated stepwise oxidation of mC to 5-hydroxymethylcyt...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Pidugu, Lakshmi S., Dai, Qing, Malik, Shuja S., Pozharski, Edwin, Drohat, Alexander C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881531/
https://ncbi.nlm.nih.gov/pubmed/31693361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10376
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