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Excision of 5-carboxylcytosine by Thymine DNA Glycosylase
5-methylcytosine (mC) is an epigenetic mark that is written by methyltransferases, erased through passive and active mechanisms, and impacts transcription, development, diseases including cancer, and aging. Active DNA demethylation involves TET-mediated stepwise oxidation of mC to 5-hydroxymethylcyt...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881531/ https://ncbi.nlm.nih.gov/pubmed/31693361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10376 |
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