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Excision of 5-carboxylcytosine by Thymine DNA Glycosylase
5-methylcytosine (mC) is an epigenetic mark that is written by methyltransferases, erased through passive and active mechanisms, and impacts transcription, development, diseases including cancer, and aging. Active DNA demethylation involves TET-mediated stepwise oxidation of mC to 5-hydroxymethylcyt...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881531/ https://ncbi.nlm.nih.gov/pubmed/31693361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10376 |
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