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Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant

The mammalian thymine DNA glycosylase (TDG) excises the mismatched base, uracil, thymine, or 5-hydroxymethyluracil (5hmU), as well as removes 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) when paired with a guanine. In the previously solved structure of TDG in complex with DNA containing 5caC...

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Detalhes bibliográficos
Main Authors: Hashimoto, Hideharu, Zhang, Xing, Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594372/
https://ncbi.nlm.nih.gov/pubmed/23337108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.013
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