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Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant
The mammalian thymine DNA glycosylase (TDG) excises the mismatched base, uracil, thymine, or 5-hydroxymethyluracil (5hmU), as well as removes 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) when paired with a guanine. In the previously solved structure of TDG in complex with DNA containing 5caC...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594372/ https://ncbi.nlm.nih.gov/pubmed/23337108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.013 |
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