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Real-Time Observation of the Initiation of RNA Polymerase II Transcription

Biochemical and structural studies have shown that the initiation of RNA polymerase II (pol II) transcription proceeds in the following stages: assembly of pol II with general transcription factors (GTFs) and promoter DNA in a “closed” preinitiation complex (PIC)(1,2); unwinding about 15 bp of the p...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Fazal, Furqan M., Meng, Cong A., Murakami, Kenji, Kornberg, Roger D., Block, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624315/
https://ncbi.nlm.nih.gov/pubmed/26331540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14882
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