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Real-Time Observation of the Initiation of RNA Polymerase II Transcription

Biochemical and structural studies have shown that the initiation of RNA polymerase II (pol II) transcription proceeds in the following stages: assembly of pol II with general transcription factors (GTFs) and promoter DNA in a “closed” preinitiation complex (PIC)(1,2); unwinding about 15 bp of the p...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Fazal, Furqan M., Meng, Cong A., Murakami, Kenji, Kornberg, Roger D., Block, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624315/
https://ncbi.nlm.nih.gov/pubmed/26331540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14882
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