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Real-Time Observation of the Initiation of RNA Polymerase II Transcription

Biochemical and structural studies have shown that the initiation of RNA polymerase II (pol II) transcription proceeds in the following stages: assembly of pol II with general transcription factors (GTFs) and promoter DNA in a “closed” preinitiation complex (PIC)(1,2); unwinding about 15 bp of the p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Fazal, Furqan M., Meng, Cong A., Murakami, Kenji, Kornberg, Roger D., Block, Steven M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624315/
https://ncbi.nlm.nih.gov/pubmed/26331540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14882
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