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Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

Recent evidence suggests that transcript elongation by RNA polymerase II (RNAPII) is regulated by mechanical cues affecting the entry into, and exit from, transcriptionally inactive states, including pausing and arrest. We present a single-molecule optical-trapping study of the interactions of RNAPI...

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Detalhes bibliográficos
Main Authors: Schweikhard, Volker, Meng, Cong, Murakami, Kenji, Kaplan, Craig D., Kornberg, Roger D., Block, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020062/
https://ncbi.nlm.nih.gov/pubmed/24733897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405181111
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