Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

Recent evidence suggests that transcript elongation by RNA polymerase II (RNAPII) is regulated by mechanical cues affecting the entry into, and exit from, transcriptionally inactive states, including pausing and arrest. We present a single-molecule optical-trapping study of the interactions of RNAPI...

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Bibliografiska uppgifter
Huvudupphovsmän: Schweikhard, Volker, Meng, Cong, Murakami, Kenji, Kaplan, Craig D., Kornberg, Roger D., Block, Steven M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020062/
https://ncbi.nlm.nih.gov/pubmed/24733897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405181111
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