Architecture of an RNA polymerase II transcription pre-initiation complex

The protein density and arrangement of subunits of a complete, 31-protein, RNA polymerase II (pol II) transcription pre-initiation complex (PIC) were determined by cryo-electron microscopy and a combination of chemical cross-linking and mass spectrometry. The PIC showed a marked division in two part...

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Bibliografische gegevens
Hoofdauteurs: Murakami, Kenji, Elmlund, Hans, Kalisman, Nir, Bushnell, David A., Adams, Christopher M., Azubel, Maia, Elmlund, Dominika, Levi-Kalisman, Yael, Liu, Xin, Levitt, Michael, Kornberg, Roger D., Gibbons, Brian J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039082/
https://ncbi.nlm.nih.gov/pubmed/24072820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1238724
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