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Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma
The c-Met protein, a transmembrane receptor tyrosine kinase, is the product of a proto-oncogene. Its only known ligand, hepatocyte growth factor (HGF), regulates cell growth, motility, migration, invasion, proliferation, and angiogenesis. The aberrant expression of c-Met is often associated with poo...
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| 出版年: | Cancer Biol Ther |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623021/ https://ncbi.nlm.nih.gov/pubmed/25801713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1026511 |
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