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Engineered Domain Swapping as an On/Off Switch for Protein Function

Domain swapping occurs when identical proteins exchange segments in reciprocal fashion. Natural swapping mechanisms remain poorly understood and engineered swapping has the potential for creating self-assembling biomaterials that encode for emergent functions. We demonstrate that induced swapping ca...

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Vydáno v:Chem Biol
Hlavní autoři: Ha, Jeung-Hoi, Karchin, Joshua M., Walker-Kopp, Nancy, Castañeda, Carlos A., Loh, Stewart N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621486/
https://ncbi.nlm.nih.gov/pubmed/26496687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.09.007
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