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Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly
Domain swapping is the process by which identical proteins exchange reciprocal segments to generate dimers. Here we introduce induced domain swapping (INDOS) as a mechanism for regulating protein function. INDOS employs a modular design consisting of the fusion of two proteins: a recognition protein...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347425/ https://ncbi.nlm.nih.gov/pubmed/28287617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44388 |
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