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Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled

Extracellular signals are often transduced by dynamic signaling complexes (“signalosomes”) assembled by oligomerizing hub proteins following their recruitment to signal-activated transmembrane receptors. A paradigm is the Wnt signalosome, which is assembled by Dishevelled via reversible head-to-tail...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Gammons, Melissa V., Renko, Miha, Johnson, Christopher M., Rutherford, Trevor J., Bienz, Mariann
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065529/
https://ncbi.nlm.nih.gov/pubmed/27692984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.08.026
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