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Engineering Domain Swapped Binding Interfaces by Mutually Exclusive Folding

Domain swapping is a mechanism for forming protein dimers and oligomers with high specificity. It is distinct from other forms of oligomerization in that the binding interface is formed by reciprocal exchange of polypeptide segments. Swapping plays a physiological role in protein-protein recognition...

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Bibliografische gegevens
Hoofdauteurs: Ha, Jeung-Hoi, Karchin, Joshua M., Walker-Kopp, Nancy, Huang, Li-Shar, Berry, Edward A., Loh, Stewart N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288482/
https://ncbi.nlm.nih.gov/pubmed/22245575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.050
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