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Engineering Domain Swapped Binding Interfaces by Mutually Exclusive Folding
Domain swapping is a mechanism for forming protein dimers and oligomers with high specificity. It is distinct from other forms of oligomerization in that the binding interface is formed by reciprocal exchange of polypeptide segments. Swapping plays a physiological role in protein-protein recognition...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288482/ https://ncbi.nlm.nih.gov/pubmed/22245575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.050 |
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